Ali Mesiwala, MD, has served as a neurosurgeon in California for more than a dozen years. Currently the chief of St. Bernardine Medical Center’s departments of surgery and neurological surgery, Dr. Ali Mesiwala has been presented with numerous awards and honors, three of which celebrated his early work on “Blood-Brain Barrier Disruption Using Ultrasound.”
For this research, Dr. Mesiwala received a first place ribbon for an oral presentation at the 2001 Congress of Neurological Surgeons, a National Research Service Award (2000-2002), and a research fellowship from the American Brain Tumor Association.
The blood-brain barrier (BBB) must be traversed in order to treat malignant brain tumors, and the use of ultrasound waves to disrupt and temporarily open this barrier has given medical professionals the ability to administer chemotherapy treatments directly to the afflicted areas of the brain.
Previous attempts to open the BBB, which include transient disruption with osmotic agents transported through the carotid arteries and intra-arterial delivery of alkylated alcohols, have had low success rates due to the difficulty of sustaining proper concentrations of the chemicals in the brain.
Treatment of a number of brain disorders may become more successful thanks to this new option for navigating the blood-brain barrier.
For this research, Dr. Mesiwala received a first place ribbon for an oral presentation at the 2001 Congress of Neurological Surgeons, a National Research Service Award (2000-2002), and a research fellowship from the American Brain Tumor Association.
The blood-brain barrier (BBB) must be traversed in order to treat malignant brain tumors, and the use of ultrasound waves to disrupt and temporarily open this barrier has given medical professionals the ability to administer chemotherapy treatments directly to the afflicted areas of the brain.
Previous attempts to open the BBB, which include transient disruption with osmotic agents transported through the carotid arteries and intra-arterial delivery of alkylated alcohols, have had low success rates due to the difficulty of sustaining proper concentrations of the chemicals in the brain.
Treatment of a number of brain disorders may become more successful thanks to this new option for navigating the blood-brain barrier.
